About us
BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 10,000 colleagues spans five continents, with administrative offices in Basel, Beijing, and Cambridge, U.S. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn and X (formerly known as Twitter).
BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
Job Description:
As BeOne Medicines continues to grow its business in Japan and across the Asia Pacific region, we are seeking a Senior Tax Manager, Japan to provide strong local and regional tax leadership and operational support.
The Senior Tax Manager, Japan & APAC will be the regional tax team's senior, hands-on lead for Japan. The role will take primary responsibility for the quality and timely delivery of Japan tax compliance, tax accounting, tax authority matters, transfer pricing execution, and day-to-day tax advice.
The role will also support selected APAC markets and regional projects. Working closely with the Associate Tax Director, global tax teams, Finance, Legal, Treasury, HR, Medical, Commercial, Clinical Operations, and external advisers, the role will translate technical requirements into practical controls, clear decisions, and sustainable processes.
The successful candidate should be technically strong, practical, detail-oriented and digitally capable, with the ability to work fluently in both Japanese and English. This role requires someone who can bridge Japanese local requirements with global tax expectations and help strengthen tax controls, documentation and process discipline.
Essential Functions of the job:
Japan tax leadership and compliance
Own and manage the Japan tax compliance calendar, tax risk register, key controls, and internal review process
Lead the preparation, coordination with external tax advisors, and review of Japanese corporate income tax, consumption tax, withholding tax, local tax, and other recurring filings, payments, registrations, and notifications
Critically review tax returns, calculations, workpapers, and advice prepared by external consultants; challenge assumptions and ensure accuracy, completeness, and consistency before internal approval or filing
Ensure tax filings and positions are supported by reliable source data, reconciled to SAP and the general ledger, and evidenced through clear, audit-ready documentation
Provide practical guidance on vendor, healthcare professional, employee, and cross-border withholding tax matters, working with the relevant process owners to establish clear responsibilities and controls
Tax accounting and reporting
Manage Japan quarterly and annual tax accounting, including current and deferred tax, tax provisions, effective tax rate analysis, return-to-provision, and uncertain tax positions, as applicable
Review tax accounts, balance sheet reconciliations, tax payments, forecasts, and cash tax requirements, and drive timely resolution of reconciling items
Support statutory financial statements, group reporting, audit requests, and tax disclosures under local requirements and US GAAP, including ASC 740 concepts
Tax audits and controversy
Act as the primary tax contact for Japan tax authority enquiries, reviews, and audits, including development of response strategies and management of information requests and deadlines
Coordinate internal stakeholders and external advisers, maintain clear records of submissions and decisions, and ensure agreed remediation actions are implemented
Transfer pricing and international tax
Manage Japan transfer pricing execution for distribution, R&D service, funding, and other related-party arrangements, including target setting, operational calculations, true-ups, and financial statement alignment
Coordinate and review benchmarking studies, local files, related-party disclosures, CbCR-related requirements, intercompany agreements, and supporting documentation
Advise on cross-border payments and transactions, including treaty access, withholding tax, permanent establishment, indirect tax, and other international tax considerations
Support Pillar Two, supply chain, customs, financing, restructuring, and other global or regional tax initiatives affecting Japan
Business partnering and transaction support
Provide timely, commercially practical tax advice on contracts, product launches, pricing, importation and distribution models, clinical trial and healthcare professional arrangements, employment matters, and business change
Partner proactively with Accounting, Accounts Payable, Treasury, Legal, HR, Payroll, Medical, Commercial, Supply Chain, and Clinical Operations to identify risks early and implement workable solutions
Clearly communicate tax positions, options, risks, and recommended actions in Japanese and English to both technical and non-technical stakeholders
APAC regional support
Support selected APAC markets on direct and indirect tax, withholding tax, tax accounting, transfer pricing, R&D incentives, tax audits, entity establishment, and other priority matters
Contribute to regional tax governance, control improvement, process standardisation, documentation, digitalisation, and tax technology initiatives
Provide cover and surge support for regional compliance cycles and projects, while maintaining Japan as the role's primary responsibility
External adviser and stakeholder management
Manage relationships with external tax advisers, including scopes of work, fee proposals, budgets, timelines, deliverable quality, and performance
Maintain internal ownership of tax positions and deliverables rather than relying solely on advisers, escalating material issues with a clear recommendation
Build trusted, constructive relationships with local management and regional and global tax stakeholders
Team support and capability development
Provide day-to-day technical guidance, review, and mentoring to the Tax Specialist and other team member(s)
Develop practical procedures, review checklists, templates, and knowledge materials to strengthen quality, continuity, and team capability
Promote a collaborative, accountable, and continuous-improvement culture across the tax team and its stakeholders
Qualification Required:
Education Required:
Bachelor's degree in Accounting, Finance, Commerce, Taxation, Law, or a related discipline
10+ years' relevant tax experience, with substantial hands-on Japan tax experience gained in a major international accounting firm and/or the in-house tax function of a multinational enterprise
Native Japanese speaker with fluent written and spoken English, and the ability to communicate complex tax matters clearly to local and global stakeholders
Formal training and strong technical grounding in Japanese corporate income tax, Japanese consumption tax, withholding tax, local taxes, tax administration, and tax audits
Strong experience in tax accounting, including current and deferred tax, tax provisions, return-to-provision analysis, tax account reconciliations, and statutory and group reporting
Working knowledge of international tax, tax treaties, transfer pricing, cross-border transactions, and tax risk management
Japanese tax qualification (Zeirishi) and/or CA, CPA, CTA, or equivalent professional qualification preferred
Experience in the pharmaceutical, biotechnology, life sciences, or another highly regulated industry preferred
Supervisory Responsibilities:
N/A
Computer Skills:
Advanced Excel skills and strong proficiency in Microsoft Office applications. Comfortable working with SAP and large data sets, and using tools such as Power Query, Power Automate, Alteryx, or similar tax and data technologies to improve controls, analytics, and efficiency.
Other Qualifications:
Strong written documentation, organisation, stakeholder management, and project management skills. Able to work effectively in a hybrid environment from Japan or Australia and collaborate across Japan and APAC time zones. Appropriate work rights for the employing location are required.
Travel:
Occasional travel within Japan and the APAC region may be required.
What We Offer To Our Valued Employees
Market competitive compensation package including performance-based annual bonus scheme
Company shares (generous welcome grant!)
In-house and external learning and development opportunities
Fantastic benefits program and keep improving!
Plus you get to work with a dynamic team of collaborative, supportive, inclusive, and fun professionals whose mission is clear: Cancer has no borders and neither do we.
Join us and Make momentum in your career!
BeOne Global Competencies
When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.
- Fosters Teamwork
- Provides and Solicits Honest and Actionable Feedback
- Self-Awareness
- Acts Inclusively
- Demonstrates Initiative
- Entrepreneurial Mindset
- Continuous Learning
- Embraces Change
- Results-Oriented
- Analytical Thinking/Data Analysis
- Financial Excellence
- Communicates with Clarity
BeOne is committed to respect and protect personal information rights of job applicants and will process job applicants’ personal information in accordance with applicable laws and regulations.
Due to BeOne’s global operation, job applicants’ data will be stored overseas with adequate protection. Besides, job applicants’ data will be stored for no longer than is necessary to facilitate potential application for other suitable positions in BeOne. For further details, please refer to BeOne’s Job Applicant Privacy Policy (https://beonemedicines.com/privacy-policy).
If you voluntarily provide your personal information to us, it is deemed as you have acknowledged and consented to (if required by the applicable laws) BeOne’s Job Applicant Privacy Policy as well as the relevant privacy terms. If you voluntarily provide the personal information of other job applicants to us, it is deemed as you have ensured that the relevant individuals have acknowledged and consented to (if required by the applicable laws) BeOne’s Job Applicant Privacy Policy as well as the relevant privacy terms.
If you have any concern, please DO NOT provide any resume or other personal information to us.


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